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Propecia
Finasteride (marketed as Proscar, Propecia, Fincar, Finpecia, Finax, Finast, Finara, Finalo, Prosteride, Gefina, Appecia, Finasterid IVAX, Finasterid Alternova) is a synthetic antiandrogen which acts by inhibiting type II 5-alpha reductase, the enzyme that converts testosterone to dihydrotestosterone (DHT). It is used as a treatment in benign prostatic hyperplasia (BPH) in low doses, and prostate cancer in higher doses. A May, 2008 study indicates that Finasteride reduces the rate of prostate cancer by 30% (see below). It is also indicated for use in combination with doxazosin therapy to reduce the risk for symptomatic progression of BPH. Additionally, it is registered in many countries for androgenetic alopecia (male-pattern baldness).
Finasteride was approved initially in 1992 as Proscar, a treatment for prostate enlargement, but the sponsor had studied 1 mg of finasteride and demonstrated hair growth in male pattern hair loss. On December 22, 1997, the USFDA approved finasteride to treat male pattern hair loss.
Based on a photographic assessment by an expert panel of dermatologists after 5 years of clinical studies. Most men see results 3 to 12 months after starting PROPECIA. aTHE FACTS ARE IN A 5-year clinical study demonstrated the effectiveness of PROPECIA.
- 9 of 10 men who took PROPECIA had visible results—either regrowth of hair (48% [134 of 279]) or no further hair loss (42% [117 of 279])—vs 25% [4 of 16] who took a placebo (sugar pill), according to an assessment of photographs by an independent panel of dermatologists.
- 2 of 3 men who took PROPECIA regrew hair, as measured by hair count. All of the men in the study who were not taking PROPECIA lost hair.
- A majority of men who took PROPECIA were rated as improved by doctors—77% (210 of 271) vs 15% (2 of 13) of men who took a placebo.
- A majority of men who took PROPECIA reported that their bald spot got smaller, their hair loss slowed down, and the appearance of their hair improved.
bIn FDA-reviewed clinical trials, 2 of 3 men who took PROPECIA regrew hair, as measured by actual hair counts, whereas all of the men in the study who did not take PROPECIA lost hair.
